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Couples' KAP Replay: Module 2, Relational Assessment

CE Hours 3

About this course

Overview

The Couple's KAP Replay is an on-demand continuing education series featuring recordings from Enamory Institute's live Couples' Ketamine-Assisted Psychotherapy (KAP) Therapist Training event held in July 2026. Through didactic instruction, clinical case examples, experiential exercises, and demonstrations, participants are provided with a structured and evidence-based approach to assessment, preparation, dosing, and integration phases of KAP with couples.

Grounded in evidence-based principles and strategies from the established couple therapy literature (Jackson et al., 2026) and informed by current research and best practices in psychedelic-assisted care, this training explores how ketamine can be thoughtfully integrated into couple therapy. Across the series, participants will learn to uncover recurring relational patterns, identify and provide feedback on relevant ketamine treatment targets, prepare couples for ketamine experiences, differentiate approaches to dyadic dosing, and facilitate targeted integration strategies to support couple therapy goals and ongoing relational change.

This training is designed to be applicable across theoretical orientations, emphasizing evidence-based couple therapy principles and structured clinical decision-making that participants can incorporate within their existing approach to working with couples. Whether taken individually or as part of the complete Couples’ KAP replay series, each module (Relational Assessment, Feedback & Preparation, Dyadic Dosing, and Dyadic Integration) provides focused instruction and practical strategies that clinicians can immediately apply in their work with couples.  


The following module provides focused instruction on one core component of KAP with couples: Relational Assessment, introducing a structured assessment and case conceptualization framework that informs subsequent KAP treatment decisions.

Module 2: Relational Assessment

Module 2, Relational Assessment, introduces assessment methods for facilitating conjoint and individual sessions in order to clarify presenting concerns and goals while also uncovering important aspects of couple interactional patterns. Therapists will learn how to map an interactional pattern between partners using thoughts, emotions, body sensations, and behaviors to understand underlying mechanisms influencing current relational distress. We then explore how the relational pattern can be used to identify relevant therapeutic targets that ketamine may support.


Learning Objectives

  • Conduct conjoint and individual assessments that elicit information to understand relational pattern & screen for safety/risk factors that would be a contraindication for KAP.
  • Map a couple’s recurring interaction pattern using a structured and evidence-based model of assessment.
  • Identify ketamine-relevant therapy targets that can inform dosing decisions and integration strategies.

Learning Levels

  • Intermediate

Target Audience

This training is suitable for clinicians and other mental health professionals with foundational knowledge of both ketamine-assisted psychotherapy (KAP) and couples therapy.

Course Instructor(s)

  • Chandra Estelle Khalifian, PhD

    Chandra Estelle Khalifian, Ph.D., is research faculty at the University of California, San Diego (UCSD) and the co-founder of Enamory– a clinic, training institute, and research center focused on psychedelic-assisted couple therapy. She earned her Ph.D. in Clinical Psychology from the University of Maryland, Baltimore County and completed her predoctoral internship and postdoctoral fellowship (Advanced Fellowship for Women’s Health) at the VA San Diego / UCSD consortium. She completed a VA Career Development Award under mentorship of Dr. Leslie Morland studying the Treatment for Relationships & Saftey (TR&ST)-- a couple-based suicide intervention that she developed during her postdoctoral fellowship. She has been a co-investigator on multiple funded research trials including a MDMA-assisted couple therapy for PTSD trial. Her research is focused on developing novel couple interventions for relationship distress, PTSD, and suicide. She is particularly interested in enhancing evidence-based interventions with psychedelics. Within Enamory, Dr. Khalifian sees couples and individuals, supervises associate therapists, conducts research, and co-developed, with her colleagues, Dr. Kayla Knopp and Dr. Skylar Kelsven, the world’s first ketamine-assisted couple therapy training and certification program.

  • Kayla Knopp, PhD

    Kayla C. Knopp, Ph.D., is a licensed clinical psychologist and clinical researcher. Her research and clinical interests center around understanding the reciprocal associations between intimate relationship functioning and mental health, supporting diverse relationship types and structures, and using novel and creative methods to improve both access to and impacts of interventions for couples. Her current projects include technology-supported interventions for couples and psychedelic-assisted couple therapies. Dr. Knopp earned her Ph.D. in Clinical Psychology from the University of Denver and completed her predoctoral internship and postdoctoral fellowship (Advanced Fellowship for Women’s Health) at the VA San Diego / University of California San Diego consortium. She was awarded a VA Career Development Award under mentorship of Dr. Leslie Morland studying the OurRelationship program for veterans and their partners. Dr. Knopp co-founded Enamory, a clinic, training institute, and research foundation specializing in ketamine-assisted couple therapy. In addition to seeing a small caseload of couples and individuals, Dr. Knopp supervises associate therapists, provides training and consultation to therapists, and conducts clinic-based research. Together with Enamory’s co-founder Dr. Chandra Khalifian and training director Dr. Skylar Kelsven, Dr. Knopp is the co-developer of the world’s first ketamine-assisted couple therapy training and certification program.

Disclosure

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS CE Learning Systems adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CE activity ― including faculty, planners, reviewers, or others ― are required to disclose all relevant financial relationships with ineligible entities (formerly known as commercial interests). The following relevant financial relationships have been disclosed by this activity’s planners, faculty, and the reviewer: PLANNERS AND REVIEWER The planners of this activity have reported that they have no relevant financial relationships. FACULTY The faculty of this activity have reported that they have no relevant financial relationships.

References

  • Alnefeesi, Y., Chen-Li, D., Krane, E., Jawad, M. Y., Rodrigues, N. B., Ceban, F., ... & Rosenblat, J. D. (2022). Real-world effectiveness of ketamine in treatment-resistant depression: A systematic review & meta-analysis. Journal of psychiatric research, 151, 693-709. https://doi.org/10.1016/j.jpsychires.2022.04.037
  • Fond, G., Loundou, A., Rabu, C., Macgregor, A., Lançon, C., Brittner, M., Micoulaud-Franchi, J. A., Richieri, R., & Leboyer, M. (2014). Ketamine administration in depressive disorders: A systematic review and meta-analysis. Psychological Medicine, 44(4), 711–723. https://doi.org/10.1017/S0033291713001572
  • Joneborg, I., Lee, Y., Di Vincenzo, J. D., Ceban, F., Meshkat, S., Lui, L. M., & McIntyre, R. S. (2022). Active mechanisms of ketamine-assisted psychotherapy: A systematic review. Journal of Affective Disorders, 315, 105–112. https://doi.org/10.1016/j.jad.2022.08.001
  • Kwan, A. T. H., Lakhani, M., Singh, G., Le, G. H., Wong, S., Teopiz, K. M., Dev, D. A., Manku, A. S., Sidhu, G., & McIntyre, R. S. (2024). Ketamine for the treatment of psychiatric disorders: A systematic review and meta-analysis. CNS Spectrums. Advance online publication. https://doi.org/10.1017/S1092852924000580
  • Reiff, C. M., Richman, E. E., Nemeroff, C. B., Carpenter, L. L., Widge, A. S., Rodriguez, C. I., & Work Group on Biomarkers and Novel Treatments, a Division of the American Psychiatric Association Council of Research. (2020). Psychedelics and psychedelic-assisted psychotherapy. American Journal of Psychiatry, 177(5), 391–410. https://doi.org/10.1176/appi.ajp.2019.19010035
  • Wagner, A. C. (2021). Couple therapy with MDMA—Proposed pathways of action. Frontiers in Psychology, 12, 733456. https://doi.org/10.3389/fpsyg.2021.733456
  • Wilkinson, S. T., Ballard, E. D., Bloch, M. H., Mathew, S. J., Murrough, J. W., Feder, A., Sos, P., Wang, G., Zarate, C. A., & Sanacora, G. (2018). The effect of a single dose of intravenous ketamine on suicidal ideation: A systematic review and individual participant data meta-analysis. American Journal of Psychiatry, 175(2), 150–158. https://doi.org/10.1176/appi.ajp.2017.17040472
  • Christensen, A., Doss, B. D., & Jacobson, N. S. (2020). Integrative behavioral couple therapy: A therapist’s guide to creating acceptance and change (2nd ed.). W. W. Norton & Company.
  • Doss, B. D., Roddy, M. K., Wiebe, S. A., & Johnson, S. M. (2022). A randomized clinical trial of emotionally focused couple therapy and integrative behavioral couple therapy for relationship distress. Journal of Marital and Family Therapy, 48(1), 283–306. https://doi.org/10.1111/jmft.12541
  • Epstein, N. B. (2024). Cognitive-behavioral couple therapy. In T. L. Sexton & J. Lebow (Eds.), Handbook of clinical couple therapy (pp. 97–124). Routledge.
  • Goldman, R., & Goldstein, Z. (2022). Case formulation in emotion-focused therapy. Journal of Clinical Psychology, 78(3), 436–453. https://doi.org/10.1002/jclp.23250
  • Halford, W. K., Hayes, S., Christensen, A., Lambert, M., Baucom, D. H., & Atkins, D. C. (2012). Toward making progress feedback an effective common factor in couple therapy. Behavior Therapy, 43(1), 49–60. https://doi.org/10.1016/j.beth.2011.01.002
  • Heatherington, L., Friedlander, M. L., & Greenberg, L. S. (2005). Change process research in couple and family therapy: Methodological challenges and opportunities. Journal of Family Psychology, 19(1), 18–27. https://doi.org/10.1037/0893-3200.19.1.18
  • Lebow, J., & Snyder, D. K. (2022). Couple therapy in the 2020s: Current status and emerging developments. Family Process, 61(4), 1359–1385. https://doi.org/10.1111/famp.12805
  • Spengler, P. M., Lee, N. A., Wiebe, S. A., & Wittenborn, A. K. (2024). A comprehensive meta-analysis on the efficacy of emotionally focused couple therapy. Couple and Family Psychology: Research and Practice, 13(2), 81–99. https://doi.org/10.1037/cfp0000233
  • Khalifian, C., Rashkovsky, K., Mitchell, E., Bismark, A., Wagner, A. C., & Knopp, K. C. (2024). A novel framework for ketamine-assisted couple therapy. Frontiers in Psychiatry, 15, 1376646. https://doi.org/10.3389/fpsyt.2024.1376646
  • Cornfield, M., McBride, S., La Torre, J. T., Zalewa, D., Gallo, J., Mahammadli, M., & Williams, M. T. (2024). Exploring effects and experiences of ketamine in group couples therapy. Journal of Psychedelic Studies, 8(2), 233–247. https://doi.org/10.1556/2054.2024.00302
  • Drozdz, S. J., Goel, A., McGarr, M. W., Katz, J., Ritvo, P., Mattina, G. F., & Ladha, K. S. (2022). Ketamine-assisted psychotherapy: A systematic narrative review of the literature. Journal of Pain Research, 15, 1691–1706. https://doi.org/10.2147/JPR.S357994
  • Avruch, D. O. (2026). Approaches to ketamine-assisted couple therapy. Frontiers in Psychology, 17, Article 1843151. https://doi.org/10.3389/fpsyg.2026.1843151
  • Jackson, J. B., Codecá, L., Miller, R. B., Simpson, J. E., O’Leary, A. M., & Renner, S. M. (2026). Empirically supported couple therapy models for couple relationship distress: A replication and update. Journal of Marital & Family Therapy, 52(4), e70162. https://doi.org/10.1111/jmft.70162

CE Process Info

Content

  • Join the Enamory Online Community & Access the Companion Training Course
    3 parts
    • LINK: Enamory Online Community Space & Companion Training Course
    • INFO: Enamory Online Community Space & Companion Training Course
    • OVERVIEW: Companion Training Course- Module 1, Background on Couple's KAP (no-CE credit)
  • Handouts- Module 2, Relational Assessment
    3 parts
    • Slide Handout- Module 2, Relational Assessment
    • Couples' KAP Quick Reference Handout
    • Enamory Assessment & Pattern Handouts
  • Assessment Part 1
    1 parts
    • Assessment Video 1
  • Assessment Part 2
    2 parts
    • Assessment Video 2
    • Pause and Reflect
  • Assessment Part 3
    2 parts
    • Assessment Video 3
    • Interaction Patterns Poll
  • Assessment Part 4
    2 parts
    • Assessment Video 4
    • Practice On Your Own
  • Assessment Part 5
    1 parts
    • Assessment Video 5

  • Joint Accreditation (JA)

    In support of improving patient care, CE Learning Systems is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

  • American Psychological Association (APA)

    Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP office maintains responsibility for the content of the programs.

  • New York Education Department's State Board for Social Work (NYEDSW)

    CE Learning Systems, LLC  (d/b/a impactce.com) is recognized by the New York State Education Department's State Board for Social Work as an approved provider of continuing education for licensed social workers. #0060.

  • New York Education Department for Licensed Mental Health Counselors (NYSEDLMHC)

    CE Learning Systems, LLC  (d/b/a impactce.com) is recognized by the New York State Education Department's State Board for Mental Health Practitioners as an approved provider of continuing education for licensed mental health counselors. #MHC-0072.

  • New York State Education Department's State Board for Psychology (NYEDPSY)

    CE Learning Systems, LLC  (d/b/a impactce.com) is recognized by the New York State Education Department's State Board for Psychology as an approved provider of continuing education for licensed psychologists. #PSY-0016.

  • New York Education Department's State Board for Marriage and Family Therapy (NYEDMFT)

    CE Learning Systems, LLC  (d/b/a impactce.com) is recognized by the New York State Education Department's State Board for Marriage and Family Therapy as an approved provider of continuing education for licensed marriage and family therapists. #MFT-0045.

Couples' KAP Replay: Module 2, Relational Assessment
You Have Completed This course
$200
You are enrolled
  • CE Hours
    3
  • Type
    Self-Paced
  • Publication Date
    Sep 1st, 2026

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